Origin
Bacopa monnieri is a plant that has been used for thousands of years in the Indian Ayurvedic tradition.
Ayurvedic medicine (from Ayur – which means life – and veda – which means knowledge) is one of the most ancient medicines recognized today by the WHO.
For Ayurvedic medicine, there is a harmonious balance between the body, mind and spirit; therefore, the mental and emotional factors of the person are considered fundamental to the development of the disorder as well as the cure.
Bacopa monnieri belongs to the Scrophulariaceae family, it is a creeping marsh plant. Area parts have been used for centuries for memory enhancement.
Bioactive principles
The main bioactive components of Bacopa monnieri are Bacosides A and B. These saponins are believed to be responsible for the pharmacological effects attributable to this species. The Bacopa present in Memorens® has a titration of 20% in Bacosides.
According to clinical studies, its mechanism of action is achieved by suppressing the activity of the enzyme acetylcholinesterase at plasma level, in addition to aneurotrophic, neuroprotective and antioxidant activity that make its use as an adaptogen of the nervous system very useful.
Therapeutic properties
Bacopa extract improves memory and cognitive function and may be useful in promoting relaxation and maintaining mental well-being.
Mechanism of action
Pre-clinical studies have shown an effect on the cholinergic system through an inhibitory action of acetylcholinesterase (AChE), an enzyme involved in the degradation of acetylcholine. Therefore, an increase in the availability of this important neurotransmitter involved in the processes of memory is generated. memory . Bacopa also has protective effects as an antioxidant and as an adaptogen (increased resistance to stress) through the normalization of the levels of plasma cortisol and some monoamines such as norepinephrine, dopamine and serotonin, in the hippocampus and cerebral cortex, ie in the areas of the brain most vulnerable to the stress .
Tolerability
Bacopa is well tolerated in children and adults. Studies have not shown any significant side effects.